SU-5402
SIGMA/SML0443 - ≥98% (HPLC)
Synonym: 3-
CAS Number: 215543-92-3
Empirical Formula (Hill Notation): C17H16N2O3
Molecular Weight: 296.32
MDL Number: MFCD08235144
Linear Formula: C17H16N2O3
Product Type: Chemical
assay | ≥98% (HPLC) |
color | light yellow to dark orange |
form | powder |
InChI | 1S/C17H16N2O3/c1-10-9-18- |
InChI key | JNDVEAXZWJIOKB-JYRVWZFOSA |
Quality Level | 100 ![]() |
SMILES string | Cc1c[nH]c(C=C2/C(=O)Nc3c |
solubility | DMSO: 10 mg/mL (clear solution) |
storage temp. | −20°C |
Application: | SU5402 has been used as a fibroblast growth factor receptor inhibitor: • in cell signalling experiments to stimulate cells for MTT (3-(4,5-dimethylthiazol-2 • to study its effect on the expression of osteogenic markers and expression of osteoprotegerin and RANKL (runt-related transcription factor(RUNX)-2 • to prepare a stock solution with DMSO (Dimethyl superoxide) for cell culture medium and also to co-treat embryos • to study its effect on osteogenic markers. |
Biochem/physiol Actions: | SU-5402 has inhibitory effect on the action of tyrosine kinases. It competitively binds to the ATP-binding site on the fibroblast growth factor receptor (FGFR). |
Biochem/physiol Actions: | SU-5402 is a FGFR antagonist and angiogenesis inhibitor. |
Features and Benefits: | This compound is a featured product for Kinase Phosphatase Biology research. Click here ![]() ![]() |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |