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Pluripotin

SIGMA/SML0444 - ≥98% (HPLC)

Synonym: N-[3-[7-(2,5-Dimethyl-2H-pyrazol-3-ylamino)-1-methyl-2-oxo-1,4-dihydro-2H-pyrimido[4,5-d]pyrimidin-3-yl]-4-methylphenyl]-3-trifluoromethyl-benzamide; SC 1; SC-1

CAS Number: 839707-37-8
Empirical Formula (Hill Notation): C27H25F3N8O2
Molecular Weight: 550.54
MDL Number: MFCD20527253
Linear Formula: C27H25F3N8O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0444-5MG 5 mg
 $194.00
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This image depicts SML0444-5MG.

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C27H25F3N8O2/c1-15-8-9-20(32-24(39)17-6-5-7-19(11-17)27(28,29)30)12-21(15)38-14-18-13-31-25(34-23(18)36(3)26(38)40)33-22-10-16(2)35-37(22)4/h5-13H,14H2,1-4H3,(H,32,39)(H,31,33,34)
InChI key NBZFRTJWEIHFPF-UHFFFAOYSA-N
Quality Level 100 
SMILES string CN1C(=O)N(Cc2cnc(Nc3cc(C)nn3C)nc12)c4cc(NC(=O)c5cccc(c5)C(F)(F)F)ccc4C
solubility DMSO: 10 mg/mL (clear solution)
storage temp. −20°C
Biochem/physiol Actions: Pluripotin is an activator of murine embryonic stem (ES) cell renewal; Dual RasGAP and ERK1 inhibitor.
Biochem/physiol Actions: Pluripotin is an activator of murine embryonic stem (ES) cell self-renewal. It appears that pluripotin mediates the activity by dual RasGAP and ERK1 inhibition.
Features and Benefits: This compound is featured on the MAPKs  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
Hazard Codes T
Risk Statements 25
Safety Statements 45
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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