Clemastine fumarate salt
SIGMA/SML0445 - ≥98% (HPLC)
Synonym: (+)-2-[2-[(p-Chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methylpyrrolidine fumarate salt; (2R)
CAS Number: 14976-57-9
Empirical Formula (Hill Notation): C21H26ClNO · C4H4O4
Molecular Weight: 459.96
EC Number: 239-055-2
MDL Number: MFCD00137486
Linear Formula: C21H26ClNO · C4H4O4
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C21H26ClNO.C4H4O4/c1-2 |
InChI key | PMGQWSIVQFOFOQ-YKVZVUFRSA |
optical activity | [α]/D +15 to +25°, c = 1 in methanol |
Quality Level | 100 ![]() |
SMILES string | OC(=O)C=CC(O)=O.CN1CCC[ |
solubility | DMSO: 5 mg/mL (clear solution; warmed) |
storage condition | desiccated |
storage temp. | room temp |
Application: | Clemastine fumarate salt has been used as a stimulator of rodent oligodendrocyte generation and myelination in vitro and in vivo. |
Biochem/physiol Actions: | Clemastine fumarate is an antihistamine H1-antagonist and anticholinergic that also has antipruritic activity. |
Features and Benefits: | This compound is featured on the Histamine Receptors ![]() ![]() |
General description: | Clemastine fumarate is used to treat multiple sclerosis, sneezing and rhinorrhea linked to common cold. It stimulates oligodendrocyte progenitor cell (OPC) differentiation and myelination. |
Packaging: | 100 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | room temp |
UNSPSC | 12352200 |