A-419259 trihydrochloride

SIGMA/SML0446 - ≥98% (HPLC)

Synonym: 7-[Trans-4-(4-methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine trihydrochloride; A419259 trihydrochloride

CAS Number: 364042-47-7 (free base)
Empirical Formula (Hill Notation): C₂₉H₃₄N₆O · 3HCl
Molecular Weight: 592.00
MDL Number: MFCD19690922
Linear Formula: C₂₉H₃₄N₆O · 3HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML0446-5MG	5 mg	$228.00 1/EA	Add To Favorites
45-SML0446-25MG	25 mg	$958.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C29H34N6O.3ClH/c1-33-15-17-34(18-16-33)22-9-11-23(12-10-22)35-19-26(27-28(30)31-20-32-29(27)35)21-7-13-25(14-8-21)36-24-5-3-2-4-6-24;;;/h2-8,13-14,19-20,22-23H,9-12,15-18H2,1H3,(H2,30,31,32);3*1H/t22-,23-;;;
InChI key	ALRMEQIQFCUAMR-KOONDFAVSA-N
Quality Level	100
SMILES string	Cl.Cl.Cl.CN1CCN(CC1)[C@H]2CC[C@@H](CC2)n3cc(-c4ccc(Oc5ccccc5)cc4)c6c(N)ncnc36
solubility	H₂O: 10 mg/mL (clear solution)
storage condition	desiccated
storage temp.	room temp

Biochem/physiol Actions:	A-419259 is a potent inhibitor of Src family kinases.
Biochem/physiol Actions:	A-419259 is a potent inhibitor of Src family kinases. IC₅₀ values for src, lck, blk, csk, fyn and lyn range between 15 and 50 nM.
Features and Benefits:	This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	room temp
UNSPSC	12352200

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