URB937

SIGMA/SML0448 - ≥95% (HPLC)

Synonym: Cyclohexylcarbamic acid 3′–carbamoyl–6–hydroxybiphenyl–3–yl ester

CAS Number: 1357160-72-5
Empirical Formula (Hill Notation): C₂₀H₂₂N₂O₄
Molecular Weight: 354.40
Linear Formula: C₂₀H₂₂N₂O₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML0448-5MG	5 mg	$105.00 1/EA	Add To Favorites
45-SML0448-25MG	25 mg	$408.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥95% (HPLC)
color	white to beige
form	powder (1:1 ratio of product to ethanol)
InChI	1S/C20H22N2O4/c21-19(24)14-6-4-5-13(11-14)17-12-16(9-10-18(17)23)26-20(25)22-15-7-2-1-3-8-15/h4-6,9-12,15,23H,1-3,7-8H2,(H2,21,24)(H,22,25)
InChI key	CMEQHOXCIGFZNJ-UHFFFAOYSA-N
Quality Level	100
SMILES string	N(C3CCCCC3)C(=O)Oc1cc(c(cc1)O)c2cc(ccc2)C(=O)N
solubility	DMSO: 15 mg/mL, clear
storage temp.	−20°C

Biochem/physiol Actions:	URB937 is a fatty acid amide hydrolase (FAAH) inhibitor that is actively excluded from the CNS by the membrane transporter ABCG2. The ED₅₀ for inhibition of FAAH activity in the brain is 200 times higher than inhibition of renal FAAH activity. In vivo administration of URB937 elevates anandamide levels in peripheral tissues, and attenuates acetic acid-induced writhing, hyperalgesia in a sciatic nerve ligation model, and pain and edema in carrageenan injected paws.
Biochem/physiol Actions:	URB937 is a fatty acid amide hydrolase (FAAH) inhibitor.
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

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