URB937
SIGMA/SML0448 - ≥95% (HPLC)
Synonym: Cyclohexylcarbamic acid 3′–carbamoyl–6–hydroxybiphenyl–3–yl ester
CAS Number: 1357160-72-5
Empirical Formula (Hill Notation): C20H22N2O4
Molecular Weight: 354.40
Linear Formula: C20H22N2O4
Product Type: Chemical
assay | ≥95% (HPLC) |
color | white to beige |
form | powder (1:1 ratio of product to ethanol) |
Quality Level | 100 ![]() |
solubility | DMSO: 15 mg/mL, clear |
storage temp. | −20°C |
Biochem/physiol Actions: | URB937 is a fatty acid amide hydrolase (FAAH) inhibitor that is actively excluded from the CNS by the membrane transporter ABCG2. The ED50 for inhibition of FAAH activity in the brain is 200 times higher than inhibition of renal FAAH activity. In vivo administration of URB937 elevates anandamide levels in peripheral tissues, and attenuates acetic acid-induced writhing, hyperalgesia in a sciatic nerve ligation model, and pain and edema in carrageenan injected paws. |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |