SM-7368

SIGMA/SML0454 - ≥98% (HPLC)

Synonym: 3-Chloro-4-nitro-N-(5-nitro-2-thiazolyl)-benzamide; SM 7368

CAS Number: 380623-76-7
Empirical Formula (Hill Notation): C₁₀H₅ClN₄O₅S
Molecular Weight: 328.69
MDL Number: MFCD00834007
Linear Formula: C₁₀H₅ClN₄O₅S
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SML0454-25MG	25 mg	$0.00 1/EA CALL FOR PRICE		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C10H5ClN4O5S/c11-6-3-5(1-2-7(6)14(17)18)9(16)13-10-12-4-8(21-10)15(19)20/h1-4H,(H,12,13,16)
InChI key	XCHLNGBTHLJLFG-UHFFFAOYSA-N
Quality Level	100
SMILES string	[O-][N+](=O)c1cnc(NC(=O)c2ccc(c(Cl)c2)[N+]([O-])=O)s1
solubility	DMSO: 10 mg/mL (clear solution)
storage temp.	2-8°C

Biochem/physiol Actions:	SM-7368 is a cell-permeable inhibitor of TNF-α-induced MMP-9 upregulation. Also, SM-7368 strongly inhibits TNF-α-induced NF-kB activity but not AP-1 activity. The compound inhibits the TNF-α-induced invasion of HT1080 human fibrosarcoma cell line.
Packaging:	5, 25 mg in glass bottle

Symbol	GHS05,GHS07
Signal word	Danger
Hazard statements	H302 - H318
Precautionary statements	P280 - P305 + P351 + P338
Hazard Codes	Xn
Risk Statements	22-41
Safety Statements	26-39
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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