SM-7368
SIGMA/SML0454 - ≥98% (HPLC)
Synonym: 3-
CAS Number: 380623-76-7
Empirical Formula (Hill Notation): C10H5ClN4O5S
Molecular Weight: 328.69
MDL Number: MFCD00834007
Linear Formula: C10H5ClN4O5S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C10H5ClN4O5S/c11-6-3-5 |
InChI key | XCHLNGBTHLJLFG-UHFFFAOYSA |
Quality Level | 100 ![]() |
SMILES string | [O-][N+](=O)c1cnc(NC(=O)c |
solubility | DMSO: 10 mg/mL (clear solution) |
storage temp. | 2-8°C |
Biochem/physiol Actions: | SM-7368 is a cell-permeable inhibitor of TNF-α-induced MMP-9 upregulation. Also, SM-7368 strongly inhibits TNF-α-induced NF-kB activity but not AP-1 activity. The compound inhibits the TNF-α-induced invasion of HT1080 human fibrosarcoma cell line. |
Packaging: | 5, 25 mg in glass bottle |
Symbol | ![]() ![]() |
Signal word | Danger |
Hazard statements | H302 - H318 |
Precautionary statements | P280 - P305 + P351 + P338 |
Hazard Codes | Xn |
Risk Statements | 22-41 |
Safety Statements | 26-39 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |