Synonym: 1,2,3,4,5,6-Hexabromocyclohexane; Benzene hexabromide; NSC 7908
CAS Number: 1837-91-8
Empirical Formula (Hill Notation): C6H6Br6
Molecular Weight: 557.54
MDL Number: MFCD00059127
Linear Formula: C6H6Br6
Product Type: Chemical
assay |
≥98% (HPLC) |
color |
white to beige |
form |
powder |
InChI |
1S/C6H6Br6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-6H |
InChI key |
QFQZKISCBJKVHI-UHFFFAOYSA-N |
Quality Level |
100 ![External link](https://krackeler.com/images/sigma/ext-link.gif) |
SMILES string |
BrC1C(Br)C(Br)C(Br)C(Br)C1Br |
solubility |
DMSO: 2 mg/mL (clear solution, warmed) |
storage temp. |
room temp |
Biochem/physiol Actions: |
1,2,3,4,5,6-hexabromocyclohexane binds directly to a pocket within the kinase domain of JAK2 and inhibits autophosphorylation. The compound also blocks growth hormone induced JAK2 autophosphorylation without affecting EFGR autophosphorylation. |
Packaging: |
50 mg in glass bottle |
Purity |
≥98% (HPLC) |
Storage Temp. |
room temp |
UNSPSC |
12352200 |