HBB2
SIGMA/SML0456 - ≥98% (HPLC)
Synonym: (1E,4E)
CAS Number: 131359-24-5
Empirical Formula (Hill Notation): C17H14O3
Molecular Weight: 266.29
MDL Number: MFCD01790784
Linear Formula: C17H14O3
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C17H14O3/c18-15(11-9-1 |
InChI key | YNVAHBUBGBLIEY-WGDLNXRISA |
Quality Level | 100 ![]() |
SMILES string | Oc1ccccc1C=CC(=O)C=Cc |
solubility | DMSO: 15 mg/mL (clear solution) |
storage temp. | −20°C |
Biochem/physiol Actions: | HBB2 is an inducer of the KEAP1/NRF2/ARE pathway that reacts with sulfhydryl groups. Also, HBB2 upregulates Hsp70 in an HSF1-dependent manner. It appears that HBB2 reacts with cysteine residues of KEAP1, which leads to activation of NRF2, and binds to Hsp90 Cys that leads to activation of HST1. |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |