Synonym: 6-Cyclohexyl-3-furan-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole; CDNG1; Cardionogen-1/vuc230
CAS Number: 577696-37-8
Empirical Formula (Hill Notation): C13H14N4OS
Molecular Weight: 274.34
MDL Number: MFCD04027630
Linear Formula: C13H14N4OS
Product Type: Chemical
assay |
≥98% (HPLC) |
color |
white to beige |
form |
powder |
InChI |
1S/C13H14N4OS/c1-2-5-9(6-3-1)12-16-17-11(10-7-4-8-18-10)14-15-13(17)19-12/h4,7-9H,1-3,5-6H2 |
InChI key |
SWTUPSNBTSPBIH-UHFFFAOYSA-N |
Quality Level |
100 ![External link](https://krackeler.com/images/sigma/ext-link.gif) |
SMILES string |
C1CCC(CC1)c2nn3c(nnc3s2)-c4ccco4 |
solubility |
DMSO: 5 mg/mL (clear solution) |
storage temp. |
2-8°C |
Biochem/physiol Actions: |
Cardionogen-1 is cardiomyocyte promoter and an inhibitor of Wnt/β-catenin dependent transcriptional activity with an EC50 of 23 nM in murine stem cells and zebrafish embryos. It induces cardiac cell formation in both murine stem cells and zebrafish embryos, expanding cardiac progenitor cells. |
Packaging: |
5, 25 mg in glass bottle |
Symbol |
GHS07 |
Signal word |
Warning |
Hazard statements |
H302 |
Hazard Codes |
Xn |
Risk Statements |
22 |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% (HPLC) |
Storage Temp. |
2-8°C |
UNSPSC |
12352200 |