Noladin ether
SIGMA/SML0473 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 222723-55-9
Empirical Formula (Hill Notation): C23H40O3
Molecular Weight: 364.56
EC Number: 200-578-6
Linear Formula: C23H40O3
Product Type: Chemical
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| assay | ≥98% (HPLC) |
| color | colorless to light yellow |
| concentration | 10 mg/mL in ethanol (1% w/v) |
| drug control | regulated under CDSA - not available from Sigma-Aldrich Canada |
| form | solution |
| InChI | 1S/C23H40O3/c1-2-3-4-5-6- |
| InChI key | CUJUUWXZAQHCNC-DOFZRALJSA |
| Quality Level | 100  |
| shipped in | dry ice |
| SMILES string | O(C(CO)CO)CCCCC=C/CC=C/ |
| storage temp. | −70°C |
| Biochem/physiol Actions: | Noladin ether (2-Arachidonyl glycerol ether) is a CB1 agonist. |
| Biochem/physiol Actions: | Noladin ether (2-Arachidonyl glycerol ether) is a stable analog of the endogenous cannabanoid 2-Arachidonylglycerol (2-AG) with selectivity for CB1 receptors. Noladin ether is a CB1 agonist. The Ki values for CB1 vs CB2 receptors are 21.2 nM and 3 mM, respectively. Noladin ether induces sedation and has modest antinociceptive activity in vivo, and reduces inter ocular pressure after administration in the eye. |
| Packaging: | 5, 25 mg in glass bottle |
| Symbol |   GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | H225 - H319 |
| Precautionary statements | P210 - P305 + P351 + P338 |
| Hazard Codes | F |
| Risk Statements | 11 |
| Safety Statements | 7-16 |
| RIDADR | UN1170 - class 3 - PG 2 - Ethanol, solution |
| WGK Germany | WGK 2 |
| Flash Point(F) | 57.2 °F - closed cup |
| Flash Point(C) | 14.0 °C - closed cup |
| Purity | ≥98% (HPLC) |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |