CGP36742

SIGMA/SML0475 - ≥97% (NMR)

Synonym: P-(3-Aminopropyl)-P-butyl-phosphinic acid; SGS 742

CAS Number: 123690-78-8
Empirical Formula (Hill Notation): C₇H₁₈NO₂P
Molecular Weight: 179.20
MDL Number: MFCD00882735
Linear Formula: C₇H₁₈NO₂P
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SML0475-5MG	5 mg	$145.00 1/EA		Add To Favorites
45-SML0475-25MG	25 mg	$488.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥97% (NMR)
color	white to beige
form	powder
InChI	1S/C7H18NO2P/c1-2-3-6-11(9,10)7-4-5-8/h2-8H2,1H3,(H,9,10)
InChI key	ONNMDRQRSGKZCN-UHFFFAOYSA-N
Quality Level	100
SMILES string	CCCCP(O)(=O)CCCN
solubility	H₂O: 10 mg/mL (clear solution, warmed)
storage condition	desiccated
storage temp.	room temp

Biochem/physiol Actions:	CGP36742 is a GABAB receptor antagonist.
Biochem/physiol Actions:	CGP36742 was the first orally active GABAB-selective antagonist. The IC₅₀ for blocking GABAergic transmission is 36 μM. Oral administration of CGP36742 in rats blocks baclofen-induced neuronal depression, and reduces learning deficit and passive avoidance in an olfactory bulbectomy depression model.
Features and Benefits:	This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Packaging:	5, 25 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302 - H319
Precautionary statements	P301 + P312 + P330 - P305 + P351 + P338
Hazard Codes	Xn
Risk Statements	22-36
Safety Statements	26
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97% (NMR)
Storage Temp.	room temp
UNSPSC	12352200

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