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Rabeprazole sodium

SIGMA/SML0476 - ≥98% (HPLC)

Synonym: 2-([4-(3-Methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl)-1H-benzo[d]imidazole; Pariprazole

CAS Number: 117976-90-6
Empirical Formula (Hill Notation): C18H20N3O3S · Na
Molecular Weight: 381.42
Linear Formula: C18H20N3O3S · Na
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML0476-10MG 10 mg
$89.00
1/EA
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45-SML0476-50MG 50 mg
$361.00
1/EA
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C18H20N3O3S.Na/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18;/h3-4,6-9H,5,10-12H2,1-2H3;/q-1;+1
InChI key KRCQSTCYZUOBHN-UHFFFAOYSA-N
Quality Level 100 
shipped in wet ice
SMILES string [Na+].COCCCOc1ccnc(CS(=O)c2nc3ccccc3[n-]2)c1C
solubility H2O: 10 mg/mL (clear solution)
storage condition desiccated
storage temp. −20°C
Application: Rabeprazole sodium has been used as a proton pump inhibitor (PPI) to study its effects on spontaneous uterine contractile activity in pregnant women.
Biochem/physiol Actions: Rabeprazole sodium is gastric proton pump inhibitor. It suppresses the production of acid in the stomach by inhibiting the gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) at the secretory surface of the gastric parietal cell. Rabeprazole sodium has been used clinically to treat acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevent gastroinetestinal bleeds associated with NSAID use.
Biochem/physiol Actions: Rabeprazole sodium is gastric proton pump inhibitor; antiulcerative.
Packaging: 10, 50 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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