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DpC

SIGMA/SML0483 - ≥98% (HPLC)

Synonym: Di-2-pyridylketone-4-cyclohexyl-4-methyl-3-thiosemicarbazone

CAS Number: 1382469-39-7
Empirical Formula (Hill Notation): C19H23N5S
Molecular Weight: 353.48
MDL Number: MFCD22666593
Linear Formula: C19H23N5S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0483-5MG 5 mg
 $168.00
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45-SML0483-25MG 25 mg
 $674.00
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C19H23N5S/c1-24(15-9-3-2-4-10-15)19(25)23-22-18(16-11-5-7-13-20-16)17-12-6-8-14-21-17/h5-8,11-15H,2-4,9-10H2,1H3,(H,23,25)
InChI key GNLZNQJBZNOUBM-UHFFFAOYSA-N
Quality Level 100 
SMILES string CN(C1CCCCC1)C(=S)NN=C(c2ccccn2)c3ccccn3
solubility DMSO: 5 mg/mL (clear solution)
storage condition protect from light
storage temp. −20°C
Biochem/physiol Actions: DpC is an iron-chelating agent.
Biochem/physiol Actions: DpC is an iron-chelating agent. In four separate human pancreatic tumor cell lines, DpC significantly increased the expression and phosphorylation of the growth and metastasis suppressor, N-myc down-stream regulated gene 1 (NDRG1) and the cdk inhibitpr p21CIP1/WAF. DpC completely blocked PANC-1 tumor growth in mouse xenografts.
Packaging: 5, 25 mg in glass bottle
Symbol GHS06  GHS06
Signal word Danger
Hazard statements H301
Precautionary statements P301 + P310
Hazard Codes T
Risk Statements 25
Safety Statements 45
RIDADR UN 2811 6.1 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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