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VU0361737

SIGMA/SML0494 - ≥98% (HPLC)

Synonym: CID-44191096; ML128; N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide

CAS Number: 1161205-04-4
Empirical Formula (Hill Notation): C13H11ClN2O2
Molecular Weight: 262.69
MDL Number: MFCD16618402
Linear Formula: C13H11ClN2O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0494-25MG 25 mg
 $259.00
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assay ≥98% (HPLC)
color white
form film
InChI 1S/C13H11ClN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17)
InChI key ARYUXFNGXHNNDM-UHFFFAOYSA-N
Quality Level 100 
SMILES string COc1cc(NC(=O)c2ccccn2)ccc1Cl
solubility DMSO: 15 mg/mL (clear solution)
storage temp. 2-8°C
Biochem/physiol Actions: VU0361737 is an mGluR4-specific positive allosteric modulator (PAM) with greater than 50 fold selectivity over other mGluR subtypes. The EC50 values for human and rat mGlu4 are 240 and 110 nM, respectively, compared to greater than 10 mM for all other mGluRs.
Biochem/physiol Actions: VU0361737 is an mGluR4-specific positive allosteric modulator (PAM).
Features and Benefits: This compound is featured on the Glutamate Receptors (G Protein Family)  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302 - H319
Precautionary statements P305 + P351 + P338
Hazard Codes Xn
Risk Statements 22-36
Safety Statements 26
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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