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GSK334429 hydrochloride

SIGMA/SML0500 - ≥98% (HPLC)

Synonym: 1-(1-Methylethyl)-4-((1-(6-(trifluoromethyl)-3-pyridinyl)-4-piperidinyl)carbonyl)hexahydro-1H-1,4-diazepine hydrochloride

CAS Number: 799558-94-4
Empirical Formula (Hill Notation): C20H29F3N4O · xHCl
Molecular Weight: 398.47 (free base basis)
MDL Number: MFCD22666404
Linear Formula: C20H29F3N4O · xHCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0500-5MG 5 mg
 $145.00
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C20H29F3N4O.ClH/c1-15(2)25-8-3-9-27(13-12-25)19(28)16-6-10-26(11-7-16)17-4-5-18(24-14-17)20(21,22)23;/h4-5,14-16H,3,6-13H2,1-2H3;1H
InChI key RCZVWLOXPFGZDD-UHFFFAOYSA-N
Quality Level 100 
SMILES string Cl.CC(C)N1CCCN(CC1)C(=O)C2CCN(CC2)c3ccc(nc3)C(F)(F)F
solubility H2O: 5 mg/mL (clear solution)
storage condition desiccated
storage temp. 2-8°C
Biochem/physiol Actions: GSK334429 is a selective histamine H3 receptor antagonist.
Biochem/physiol Actions: GSK334429 is a selective histamine H3 receptor antagonist. H3 antagonists increase the release of brain histamine, ACh, NE and DA neurotransmitters that modulate cognitive processes. Studies look at their analgesic efffects including efficacy for neuropathic pain.
Features and Benefits: This compound is featured on the Histamine Receptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Other Notes: Store desiccated; dry room.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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