9(S)-HODE
SIGMA/SML0503 - ≥98% (HPLC)
Synonym: 9S-
CAS Number: 73543-67-6
Empirical Formula (Hill Notation): C18H32O3
Molecular Weight: 296.44
EC Number: 200-578-6
MDL Number: MFCD00065831
Linear Formula: C18H32O3
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | colorless to light yellow |
| concentration | 1 mg/mL in ethanol |
| form | solution |
| InChI | 1S/C18H32O3/c1-2-3-4-5-6- |
| InChI key | NPDSHTNEKLQQIJ-UINYOVNOSA |
| Quality Level | 100  |
| shipped in | wet ice |
| SMILES string | CCCCC/C=CC=C[C@@H](O)CC |
| storage temp. | −20°C |
| Biochem/physiol Actions: | 9(S)-HODE is a pro-inflammatory linoleic acid lipoxygenation product. |
| Biochem/physiol Actions: | 9(S)-HODE is produced by the lipoxygenation of linoleic acid. It is a major component of plasma oxidized low-density lipoprotein. 9-HODE has been shown to stimulate cell proliferation and and extracellular matrix synthesis in human mesangial cells via PPARgamma. Pro-inflammatory effects of 9-HODE, acting through the receptor GPR132, can contribute to atherosclerosis progression. 9-HODE has also been shown to activate spinal TRPV1, leading to inflammatory hyperalgesia. |
| Packaging: | 100, 500 μg in glass bottle |
| Symbol |   GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | H225 - H319 |
| Precautionary statements | P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338 |
| Hazard Codes | F |
| Risk Statements | 11 |
| Safety Statements | 7-16 |
| RIDADR | UN1170 - class 3 - PG 2 - Ethanol, solution |
| WGK Germany | WGK 1 |
| Flash Point(F) | 57.2 °F - closed cup |
| Flash Point(C) | 14.0 °C - closed cup |
| Purity | ≥98% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 51111800 |