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GNF-5

SIGMA/SML0511 - ≥98% (HPLC)

Synonym: N-(2-Hydroxyethyl)-3-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide

CAS Number: 778277-15-9
Empirical Formula (Hill Notation): C20H17F3N4O3
Molecular Weight: 418.37
MDL Number: MFCD16877246
Linear Formula: C20H17F3N4O3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0511-5MG 5 mg
 $143.00
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C20H17F3N4O3/c21-20(22,23)30-16-6-4-15(5-7-16)27-18-11-17(25-12-26-18)13-2-1-3-14(10-13)19(29)24-8-9-28/h1-7,10-12,28H,8-9H2,(H,24,29)(H,25,26,27)
InChI key IIQUYGWWHIHOCF-UHFFFAOYSA-N
Quality Level 100 
SMILES string OCCNC(=O)c1cccc(c1)-c2cc(Nc3ccc(OC(F)(F)F)cc3)ncn2
solubility DMSO: 10 mg/mL (clear solution)
storage temp. 2-8°C
Biochem/physiol Actions: BRC-Abl inhibitor
Biochem/physiol Actions: GNF-5 is a BRC-Abl inhibitor.
Features and Benefits: This compound is a featured product for Kinase Phosphatase Biology research. Click here  to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound is featured on the Abl  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Other Notes: GNF-5 has been expertly reviewed and recommended by the Chemical Probes Portal. For more information, please visit the GNF-5 probe summary  on the Chemical Probes Portal website.
Packaging: 5, 25 mg in glass bottle
Hazard Codes T
Risk Statements 25-36
Safety Statements 22-45
RIDADR UN 2811 6.1 / PGIII
WGK Germany WGK 3
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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