Amlexanox

SIGMA/SML0517 - ≥98% (HPLC)

Synonym: 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]Benzopyrano[2,3-b]pyridine-3-carboxylic acid; AA 673; Amoxanox; CHX 3673

CAS Number: 68302-57-8
Empirical Formula (Hill Notation): C₁₆H₁₄N₂O₄
Molecular Weight: 298.29
MDL Number: MFCD00864790
Linear Formula: C₁₆H₁₄N₂O₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML0517-10MG	10 mg	$116.00 1/EA	Add To Favorites
45-SML0517-50MG	50 mg	$464.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21)
InChI key	SGRYPYWGNKJSDL-UHFFFAOYSA-N
Quality Level	100
shipped in	wet ice
SMILES string	CC(C)c1ccc2Oc3nc(N)c(cc3C(=O)c2c1)C(O)=O
solubility	DMSO: 10 mg/mL at warmed, clear
storage temp.	−20°C

Biochem/physiol Actions:	Amlexanox elevates the amount of nonsense-containing mRNAs in treated cells and helps to generate full-length proteins effectively.
Biochem/physiol Actions:	Amlexanox is an anti-allergy and anti-asthma drug that blocks histamine and leukotriene release from leukocytes and mast cells. Amlexanox has also been shown to inhibit cahaperone activity of Hsp90, and S100A13, which is involved in transport of proteins devoid of signal peptide sequences.
Biochem/physiol Actions:	Amlexanox is an anti-allergy, anti-ulcer drug; S100A13 inhibitor.
General description:	Amlexanox is an anti-allergic drug with anti-inflammatory properties.
Packaging:	10, 50 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Hazard Codes	Xn
Risk Statements	22-43
Safety Statements	36/37
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

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