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Amlexanox

SIGMA/SML0517 - ≥98% (HPLC)

Synonym: 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]Benzopyrano[2,3-b]pyridine-3-carboxylic acid; AA 673; Amoxanox; CHX 3673

CAS Number: 68302-57-8
Empirical Formula (Hill Notation): C16H14N2O4
Molecular Weight: 298.29
MDL Number: MFCD00864790
Linear Formula: C16H14N2O4
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML0517-10MG 10 mg
$108.00
1/EA
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45-SML0517-50MG 50 mg
$433.00
1/EA
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21)
InChI key SGRYPYWGNKJSDL-UHFFFAOYSA-N
Quality Level 100 
shipped in wet ice
SMILES string CC(C)c1ccc2Oc3nc(N)c(cc3C(=O)c2c1)C(O)=O
solubility DMSO: 10 mg/mL at warmed, clear
storage temp. −20°C
Biochem/physiol Actions: Amlexanox elevates the amount of nonsense-containing mRNAs in treated cells and helps to generate full-length proteins effectively.
Biochem/physiol Actions: Amlexanox is an anti-allergy and anti-asthma drug that blocks histamine and leukotriene release from leukocytes and mast cells. Amlexanox has also been shown to inhibit cahaperone activity of Hsp90, and S100A13, which is involved in transport of proteins devoid of signal peptide sequences.
Biochem/physiol Actions: Amlexanox is an anti-allergy, anti-ulcer drug; S100A13 inhibitor.
General description: Amlexanox is an anti-allergic drug with anti-inflammatory properties.
Packaging: 10, 50 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Hazard Codes Xn
Risk Statements 22-43
Safety Statements 36/37
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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