GRI977143

SIGMA/SML0544 - ≥98% (HPLC)

Synonym: 2-[[3-(1,3-Dioxo-1H-benz[de]isoquinolin-2(3H)-yl)propyl]thio]-benzoic acid

CAS Number: 325850-81-5
Empirical Formula (Hill Notation): C₂₂H₁₇NO₄S
Molecular Weight: 391.44
Linear Formula: C₂₂H₁₇NO₄S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML0544-5MG	5 mg	$142.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to light brown
form	powder
InChI	1S/C22H17NO4S/c24-20-16-9-3-6-14-7-4-10-17(19(14)16)21(25)23(20)12-5-13-28-18-11-2-1-8-15(18)22(26)27/h1-4,6-11H,5,12-13H2,(H,26,27)
InChI key	GMVZUCHUOYUMLL-UHFFFAOYSA-N
Quality Level	100
SMILES string	S(CCC[n]2[c](c3c4c([c]2=O)cccc4ccc3)=O)c1c(cccc1)C(=O)O
solubility	DMSO: 10 mg/mL, clear
storage temp.	2-8°C

Biochem/physiol Actions:	GRI977143 is a potent, specific LPA2 receptor agonist with no affinity for other LPA receptors. GRI977143 inhibits the initiation of apoptosis induced by adriamycin or serum withdrawal in MEFs derived from LPA2 knock-out mice transfected with an LPA2 expression vector, but has no affect in non-transfected cells.
Biochem/physiol Actions:	GRI977143 is a potent, specific LPA2 receptor agonist.
Packaging:	5, 25 mg in glass bottle

Symbol	GHS07,GHS09
Signal word	Warning
Hazard statements	H302 - H410
Precautionary statements	P273 - P301 + P312 + P330
Hazard Codes	Xn,N
Risk Statements	22-43-50/53
Safety Statements	36/37-60-61
RIDADR	UN 3077 9 / PGIII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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