Synonym: N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-benzamide hydrochloride
CAS Number: 1217756-94-9
Empirical Formula (Hill Notation): C21H22FN3O · HCl
Molecular Weight: 387.88
Linear Formula: C21H22FN3O · HCl
Product Type: Chemical
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| assay |
≥98% (HPLC) |
| color |
white to beige |
| form |
powder |
| InChI |
1S/C21H22FN3O.ClH/c1-25(2)16-8-10-20-18(12-16)17-11-15(7-9-19(17)24-20)23-21(26)13-3-5-14(22)6-4-13;/h3-7,9,11,16,24H,8,10,12H2,1-2H3,(H,23,26);1H/t16-;/m1./s1 |
| InChI key |
OKUHLSYESBLBCP-PKLMIRHRSA-N |
| Quality Level |
100  |
| SMILES string |
Fc1ccc(cc1)C(=O)Nc2cc3c([nH]c4c3C[C@@H](CC4)N(C)C)cc2.Cl |
| solubility |
H2O: 10 mg/mL, clear |
| storage condition |
desiccated |
| storage temp. |
2-8°C |
| Biochem/physiol Actions: |
LY344864 hydrochloride is a potent and selective 5-HT1F receptor agonist. |
| Biochem/physiol Actions: |
LY344864 hydrochloride is a potent and selective 5-HT1F receptor agonist. It has an EC50 of 3 nM, and displays > 80-fold selectivity over other 5-HT receptors |
| Biochem/physiol Actions: |
LY344864 might be useful in the treatment approach for migraine. LY344864 is found to prevent the extravasation of dura protein and reduce c-fos like immunoreactions induced by capsaicin. |
| Packaging: |
5, 25 mg in glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |