BETP
SIGMA/SML0558 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 1371569-69-5
Empirical Formula (Hill Notation): C20H17F3N2O2S
Molecular Weight: 406.42
MDL Number: MFCD23143626
Linear Formula: C20H17F3N2O2S
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white to beige |
| form | powder |
| InChI | 1S/C20H17F3N2O2S/c1-2-28( |
| InChI key | NTDFYGSSDDMNHI-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | CCS(=O)c1nc(cc(n1)C(F)(F) |
| solubility | DMSO: 5 mg/mL, clear (warmed) |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | BETP is a GLP-1 receptor allosteric modulator. |
| Biochem/physiol Actions: | BETP is a positive allosteric modulator of the GLP-1 receptor that potentiates cAMP accumulation and glucose-dependent insulin release in pancreatic islet cells, in the presence of the weak GLP-1 metabolite, GLP-1(9-36). BETP has additive effects on the endogenous GLP-1 receptor ligand GLP-1(7-36). |
| Biochem/physiol Actions: | BetP is a trimeric Na+-coupled betaine symporter. BetP belongs to the betaine-choline-carnitine transporter (BCCT) family. It controls transport activity in dependence of the cytoplasmic K+-concentration. |
| Packaging: | 5, 25 mg in glass bottle |
| Hazard Codes | Xi |
| Risk Statements | 36 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 51111800 |