Synonym: (4Z,7Z,10Z,13Z,16Z,19Z)-N-(2-Hydroxyethyl)docosa-4,7,10,13,16,19-hexaenamide; DEA; DHEA; N-(2-Hydroxyethyl)-4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenamide; N-Docosahexaenoylethanolamide
CAS Number: 162758-94-3
Empirical Formula (Hill Notation): C24H37NO2
Molecular Weight: 371.56
Linear Formula: C24H37NO2
Product Type: Chemical
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| assay |
≥98% (HPLC) |
| color |
colorless to yellow |
| drug control |
regulated under CDSA - not available from Sigma-Aldrich Canada |
| form |
ethanol solution (5 mg/ml) |
| Quality Level |
100  |
| shipped in |
dry ice |
| storage temp. |
−20°C |
| Biochem/physiol Actions: |
Docosahexaenoyl ethanolamide (DHEA) has the ability to block the proliferation of head and neck squamous cell carcinoma (HNSCC) cell. |
| Biochem/physiol Actions: |
Docosahexaenoyl ethanolamide (DHEA) is a lipid signaling molecule present in brain and retina at concentrations, similar to those for arachidonoyl ethanolamide. DHEA binds to the rat brain CB1 receptor with a Ki of 324 nM. It exhibits anti-inflammatory and organ protective activity. Studies show that docosahexaenoyl ethanolamide is the mediator of neurite growth and synaptogenesis in hippocampal neurons, resulting in enhanced synaptic activity. |
| Biochem/physiol Actions: |
Docosahexaenoyl ethanolamide (DHEA), a lipid signaling molecule, binds to the rat brain CB1 receptor and exhibits anti-inflammatory and organ protective activity. |
| Features and Benefits: |
This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Packaging: |
5, 25 mg in glass bottle |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
−20°C |
| UNSPSC |
12352211 |