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PD153035 hydrochloride

SIGMA/SML0564 - ≥98% (HPLC)

Synonym: 4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline hydrochloride; AG 1517; PD 153035; SU 5271; ZM 252868

CAS Number: 183322-45-4
Empirical Formula (Hill Notation): C16H14BrN3O2 · HCl
Molecular Weight: 396.67
MDL Number: MFCD01074805
Linear Formula: C16H14BrN3O2 · HCl
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML0564-5MG 5 mg
$102.00
1/EA
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45-SML0564-25MG 25 mg
$410.00
1/EA
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C16H14BrN3O2.ClH/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11;/h3-9H,1-2H3,(H,18,19,20);1H
InChI key ZJOKWAWPAPMNIM-UHFFFAOYSA-N
Quality Level 100 
SMILES string Cl.COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC
solubility DMSO: 2 mg/mL, clear (warmed)
storage condition desiccated
storage temp. 2-8°C
Biochem/physiol Actions: PD153035 is an EGFR tyrosine kinase inhibitor.
Biochem/physiol Actions: PD153035 is apotent and selective ATP competitive inhibitor of the epidermal growth factor receptor tyrosine kinase EGFR.
Features and Benefits: This compound is a featured product for Kinase Phosphatase Biology research. Click here  to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound is featured on the EGFR  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 51111800

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