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BRD4770

SIGMA/SML0567 - ≥98% (HPLC)

Synonym: 2-(Benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic acid methyl ester

CAS Number: 1374601-40-7
Empirical Formula (Hill Notation): C25H23N3O3
Molecular Weight: 413.47
MDL Number: MFCD23143627
Linear Formula: C25H23N3O3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0567-5MG 5 mg
 $142.00
1/EA		 Add To Favorites
45-SML0567-25MG 25 mg
 $546.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C25H23N3O3/c1-31-24(30)20-14-15-22-21(17-20)26-25(27-23(29)19-12-6-3-7-13-19)28(22)16-8-11-18-9-4-2-5-10-18/h2-7,9-10,12-15,17H,8,11,16H2,1H3,(H,26,27,29)
InChI key UCGWYCMPZXDHNR-UHFFFAOYSA-N
Quality Level 100 
SMILES string O=C(C1=CC=CC=C1)NC2=NC3=C(N2CCCC4=CC=CC=C4)C=CC(C(OC)=O)=C3
solubility DMSO: 5 mg/mL, clear (warmed)
storage temp. 2-8°C
Biochem/physiol Actions: BRD4770 is a selective inhibitor of the histone methyltransferase G9a.
Biochem/physiol Actions: BRD4770 is a selective inhibitor of the histone methyltransferase G9a. BRD4770 blocks lysine residue 9 methylation of histone H3 without inducing apoptosis. In PANC-1 cells, BRD4770 activates the ataxia telangiectasia mutated (ATM) pathway, induces senescence and inhibits anchorage-dependent and -independent growth.
Packaging: 5, 25 mg in glass bottle
Hazard Codes Xn
Risk Statements 22
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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