NNGH

SIGMA/SML0584 - ≥98% (HPLC)

Synonym: BML-205; N-Isobutyl-N-(4-methoxyphenylsulfonyl)glycyl hydroxamic acid

CAS Number: 161314-17-6
Empirical Formula (Hill Notation): C₁₃H₂₀N₂O₅S
Molecular Weight: 316.37
MDL Number: MFCD02179370
Linear Formula: C₁₃H₂₀N₂O₅S
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SML0584-5MG	5 mg	$122.00 1/EA		Add To Favorites
45-SML0584-25MG	25 mg	$324.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C13H20N2O5S/c1-10(2)8-15(9-13(16)14-17)21(18,19)12-6-4-11(20-3)5-7-12/h4-7,10,17H,8-9H2,1-3H3,(H,14,16)
InChI key	JIRXORZYIXSWOB-UHFFFAOYSA-N
Quality Level	100
SMILES string	COc1ccc(cc1)S(=O)(=O)N(CC(C)C)CC(=O)NO
solubility	DMSO: 15 mg/mL, clear
storage temp.	2-8°C

Biochem/physiol Actions:	NNGH is a potent and cell-permeable inhibitor of matrix metalloproteinase 3 (MMP-3,stromelysin 1, progelatinase).
Biochem/physiol Actions:	NNGH is a potent and cell-permeable inhibitor of matrix metalloproteinase 3 (MMP-3,stromelysin 1, progelatinase). NNGH has been used to inhibit MMP-3 in a variety of studies. Inhibition of MMP-3 with NNGH significantly suppressed the expression of iNOS and pro-inflammatory cytokines and the activities of NF-KB, AP-1, and MAPK in LPS-stimulated microglia, suggesting a role for MMP-3 in neuroinflammation.
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

Choose a favorite list for this item:

Catalog Number	Description	Price

		$

Please choose a list :

Continue Shopping

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.