Synonym: 1,4-Dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrol[3,2-b]pyridin-5-one dihydrochloride; 3- (1,2,5,6-Tetrahydro-4-pyridyl)-5-propoxypyrrolo[3, 2-b] pyridine hydrochloride; 5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine hydrochloride; CP-94253 hydrochloride
CAS Number: 131084-35-0 (free base)
Empirical Formula (Hill Notation): C15H19N3O · 2HCl
Molecular Weight: 330.25
Linear Formula: C15H19N3O · 2HCl
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white to beige |
| form |
powder |
| InChI |
1S/C15H19N3O.2ClH/c1-2-9-19-14-4-3-13-15(18-14)12(10-17-13)11-5-7-16-8-6-11;;/h3-5,10,16-17H,2,6-9H2,1H3;2*1H |
| InChI key |
HGFPLQPNCZQRLO-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
Cl.Cl.CCCOc1ccc2[nH]cc(C3=CCNCC3)c2n1 |
| solubility |
H2O: 15 mg/mL, clear |
| storage condition |
desiccated |
| storage temp. |
room temp |
| Biochem/physiol Actions: |
CP-94,253 is a potent and selective serotonin 5-HT1B receptor agonist with approximately 25x and 40x selectivity over the closely related 5-HT1D and 5-HT1A receptors. Ki values are 89, 2, 860, 49 and 1,600 nM for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D and 5-HT2 receptors respectively. CP-94,253 was found to be anxiolytic in animal models; dose-dependently enhanced reinforcing effects of cocaine (self-administration);and reduced food intake. |
| Biochem/physiol Actions: |
CP-94,253 is a potent and selective serotonin 5-HT1B receptor agonist. |
| Packaging: |
5, 25 mg in glass bottle |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
room temp |
| UNSPSC |
12352200 |
GHS07