CGP52432
SIGMA/SML0593 - ≥98% (HPLC)
Synonym: [3-
CAS Number: 139667-74-6
Empirical Formula (Hill Notation): C15H24Cl2NO4P
Molecular Weight: 384.24
Linear Formula: C15H24Cl2NO4P
Product Type: Chemical
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| assay | ≥98% (HPLC) |
| color | white to beige |
| form | powder |
| InChI | 1S/C15H24Cl2NO4P/c1-3-21- |
| InChI key | GJZVQXWEIYRHBE-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | [P](=O)(O)(C(OCC)OCC)CCCN |
| solubility | H2O: 1 mg/mL, clear (warmed) |
| storage condition | desiccated |
| storage temp. | 2-8°C |
| Application: | CGP52432 has been used as a γ-aminobutyric acid B (GABAB) antagonist: • to study its effects on the simulation of the onset of status epilepticus (SE) in mice • for voltage-clamp recording in mice neurons • to study its effects on the GABAB receptor-mediated neurotransmission in guinea pig hippocampus |
| Biochem/physiol Actions: | CGP52432 is a very potent antagonist of GABAB receptors. |
| Biochem/physiol Actions: | CGP52432 is a very potent antagonist of GABAB receptors. (IC50 = 85 nM). |
| Biochem/physiol Actions: | CGP52432 participates in inhibiting the glycine overflow in the hippocampus. |
| Features and Benefits: | This compound is featured on the GABAB Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Other Notes: | Do not freeze. |
| Packaging: | 5, 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |