DIF-1
SIGMA/SML0599 - ≥98% (HPLC)
Synonym: 1-
CAS Number: 111050-72-7
Empirical Formula (Hill Notation): C13H16Cl2O4
Molecular Weight: 307.17
Linear Formula: C13H16Cl2O4
Product Type: Chemical
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| assay | ≥98% (HPLC) |
| color | white to beige |
| form | powder |
| InChI | 1S/C13H16Cl2O4/c1-3-4-5-6 |
| InChI key | VUDQSRFCCHQIIU-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | Clc1c(c(c(c(c1O)C(=O)CCCC |
| solubility | DMSO: 20 mg/mL, clear |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | DIF-1 (differentiation-inducing factor-1) is isolated from a Dictyostelium slime mold, and is used to inhibit proliferation/promote differentiation in various cell lines. |
| Biochem/physiol Actions: | DIF-1 is a cell differentiation inducing factor. |
| Biochem/physiol Actions: | DIF-1 is a cell differentiation inducing factor. Differentiation-inducing factor-1 (DIF-1) blocks the migration and invasion of cells and decreases the expression of matrix metalloproteinase-2. It prevents the proliferation of cells using glycogen synthase kinase-3 (GSK-3)-dependent mechanism. DIF-1 is more active when compared to DIF-2 in promoting stalk cell differentiation under submerged assay conditions. |
| Packaging: | 5, 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |