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AF-DX 384 Free Base

SIGMA/SML0620 - ≥98% (HPLC)

Synonym: N-[2-[2-[(Dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide

CAS Number: 118290-26-9
Empirical Formula (Hill Notation): C27H38N6O2
Molecular Weight: 478.63
Linear Formula: C27H38N6O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0620-5MG 5 mg
 $103.02
1/EA		 Add To Favorites
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: SML0620-5MG.

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C27H38N6O2/c1-3-16-31(17-4-2)20-21-10-7-8-18-32(21)19-15-29-27(35)33-24-13-6-5-11-22(24)26(34)30-23-12-9-14-28-25(23)33/h5-6,9,11-14,21H,3-4,7-8,10,15-20H2,1-2H3,(H,29,35)(H,30,34)
InChI key MZDYABXXPZNUCT-UHFFFAOYSA-N
Quality Level 100 
SMILES string N4(C(CCCC4)CN(CCC)CCC)CCNC(=O)[n]1c2ncccc2[nH][c](c3c1cccc3)=O
solubility DMSO: 10 mg/mL, clear (warmed)
storage temp. room temp
Biochem/physiol Actions: AF-DX 384 Free Base is a muscarinic M2/M4 receptor selective antagonist.
Biochem/physiol Actions: AF-DX 384 Free Base is a potent muscarinic M2/M4 receptor selective antagonist (pKi values are 8.22, 8.00, 7.51, 7.18 and 6.27 at human M2, M4, M1, M3 and M5 receptors respectively).
Features and Benefits: This compound is a featured product for Neuroscience research. Click here  to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound is featured on the Acetylcholine Receptors (Muscarinic)  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352200

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