Synonym: 3-Fluoro-1,2-phenylene bis(3-hydroxybenzoate); 3-Hydroxy-benzoic acid 1,1′-(3-fluoro-1,2-phenylene) ester
CAS Number: 1223397-11-2
Empirical Formula (Hill Notation): C20H13FO6
Molecular Weight: 368.31
MDL Number: MFCD24387113
Linear Formula: C20H13FO6
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white to beige |
| form |
powder |
| InChI |
1S/C20H13FO6/c21-16-8-3-9-17(26-19(24)12-4-1-6-14(22)10-12)18(16)27-20(25)13-5-2-7-15(23)11-13/h1-11,22-23H |
| InChI key |
FRSWCCBXIHFKKY-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
O=C(C1=CC=CC(O)=C1)OC2=C(F)C=CC=C2OC(C3=CC(O)=CC=C3)=O |
| solubility |
DMSO: 20 mg/mL, clear |
| storage condition |
desiccated |
| storage temp. |
2-8°C |
| Application: |
WZB-117 has been used to study its tumor initiating ability in cancer stem cells. It has also been used to study the effect of glucose antagonists on 2-NBDG (2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose) uptake. |
| Biochem/physiol Actions: |
WBZ 117 is an inhibitor of basal glucose transport in H1299 lung and other cancer cells. |
| Biochem/physiol Actions: |
WBZ 117 is an inhibitor of basal glucose transport. |
| Biochem/physiol Actions: |
WZB-117 is an irreversible inhibitor. In cancer cells, WZB-117 prevents cell growth by stimulating apoptosis in any glucose concentration. It targets self-renewal and tumor-initiating capacity in cancer stem cells. |
| Packaging: |
5, 25 mg in glass bottle |
| Hazard Codes |
N |
| Risk Statements |
50 |
| Safety Statements |
61 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |
