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8-Aminoadenosine

SIGMA/SML0628 - ≥98% (HPLC)

Synonym: 6,8-Diamino-9-β-D-ribofuranosyl-9H-purine; 8-Amino Adenosine; 8-Amino-Adenosine; 8-NH2-Ado; NSC 90394

CAS Number: 3868-33-5
Empirical Formula (Hill Notation): C10H14N6O4
Molecular Weight: 282.26
Linear Formula: C10H14N6O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0628-10MG 10 mg
 $111.00
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45-SML0628-50MG 50 mg
 $296.00
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This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C10H14N6O4/c11-7-4-8(14-2-13-7)16(10(12)15-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,15)(H2,11,13,14)
InChI key DVGWFQILDUEEGX-UHFFFAOYSA-N
Quality Level 100 
SMILES string [n]2(c3ncnc(c3nc2N)N)C1OC(C(C1O)O)CO
solubility H2O: 2 mg/mL, clear (warmed)
storage temp. −20°C
Biochem/physiol Actions: 8-Aminoadenosine, a ribose nucleoside, reduces cellular ATP levels and inhibits mRNA synthesis. 8-Aminoadenosine also inhibits transcription and polyadenylation. 8-Aminoadenosine potently inhibits varies breast cancer cell lines proliferation and activates cell death independent of p53. 8-NH2-Ado is highly cytotoxic to other cancer cell lines.
Biochem/physiol Actions: 8-Aminoadenosine, a transcription inhibitor, reduces cellular ATP levels and inhibits mRNA synthesis.
Packaging: 10, 50 mg in glass bottle
Symbol GHS06  GHS06
Signal word Danger
Hazard statements H301
Precautionary statements P301 + P310
Hazard Codes T
Risk Statements 25
Safety Statements 45
RIDADR UN 2811 6.1 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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