Mitochondrial Fusion Promoter M1
SIGMA/SML0629 - ≥95% (HPLC)
Synonym: (E)
CAS Number: 219315-22-7
Empirical Formula (Hill Notation): C14H10Cl4N2O
Molecular Weight: 364.05
Linear Formula: C14H10Cl4N2O
Product Type: Chemical
| assay | ≥95% (HPLC) |
| color | white to beige |
| form | powder |
| InChI key | WMAGOVJOXMBLHY-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | Clc1c(c(cc(c1)Cl)Cl)NNC(= |
| solubility | DMSO: 10 mg/mL, clear |
| storage temp. | 2-8°C |
| Application: | Mitochondrial Fusion Promoter M1 has been used as a fusion promoter: • to study its effects on peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α expression in breast cancer cells • to study the link between nucleoside diphosphate kinase 3 (NME3)-regulated mitochondrial fluctuations and stability of genome in NME3 knockdown cells • to study its effects on mitochondrial fusion in neuronal cells |
| Biochem/physiol Actions: | Mitochondrial Fusion Promoter M1 is a cell permeable hydrazone that enhances mitochondrial fusion. |
| Biochem/physiol Actions: | Mitochondrial Fusion Promoter M1 is a cell permeable hydrazone that enhances mitochondrial fusion. M1 protects cells from mitochondrial fragmentation associated cell death. Mitochondrial Fusion Promoter M1 does not interfere with endoplasmic reticula (ER) and lysosomes morphology. |
| Packaging: | 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |