Synonym: 4-(2-Aminoethoxy)-N2,N6-bis[4-(2-aminoethoxy)-2-quinolinyl]-2,6-pyridinedicarboxamide trifluoroacetate salt; RR82 trifluoroacetate salt
CAS Number: 1085412-37-8 (free base)
Empirical Formula (Hill Notation): C31H32N8O5 · xC2HF3O2
Molecular Weight: 596.64 (free base basis)
MDL Number: MFCD26142941
Linear Formula: C31H32N8O5 · xC2HF3O2
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white to beige |
| form |
powder |
| InChI |
1S/C31H32N8O5.C2HF3O2/c32-9-12-42-19-15-24(30(40)38-28-17-26(43-13-10-33)20-5-1-3-7-22(20)36-28)35-25(16-19)31(41)39-29-18-27(44-14-11-34)21-6-2-4-8-23(21)37-29;3-2(4,5)1(6)7/h1-8,15-18H,9-14,32-34H2,(H,36,38,40)(H,37,39,41);(H,6,7) |
| InChI key |
SLFYRKZWSPFGQZ-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
OC(C(F)(F)F)=O.O=C(NC1=CC(OCCN)=C(C=CC=C2)C2=N1)C3=CC(OCCN)=CC(C(NC4=NC(C=CC=C5)=C5C(OCCN)=C4)=O)=N3 |
| solubility |
H2O: 15 mg/mL, clear |
| storage condition |
protect from light |
| storage temp. |
−20°C |
| Application: |
Pyridostatin trifluoroacetate salt has been used as a G-quadruplex (G4) stabilizer to study interactions between RNA G4 and ligand molecules. |
| Biochem/physiol Actions: |
Pyridostatin is a highly selective G-quadruplex interacting molecule. It retards the growth of human cancer cells by inducing replication/transcription dependent on DNA damage. |
| Biochem/physiol Actions: |
Pyridostatin stabilizes G-quadruplexes, targeting the proto-oncogene SRC and telomeric G-quadruplexes, inducing DNA damage and cell-cycle arrest. |
| Biochem/physiol Actions: |
Pyridostatin stabilizes G-quadruplexes. |
| Other Notes: |
Light sensitive |
| Packaging: |
5, 25 mg in glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
−20°C |
| UNSPSC |
12352202 |
