DDRI-18
SIGMA/SML0710 - ≥98% (HPLC)
Synonym: 3,3′-[6,6′-bi-1H-Benzimidazole]-2,2′-diylbis-benzenamine
CAS Number: 4402-18-0
Empirical Formula (Hill Notation): C26H20N6
Molecular Weight: 416.48
MDL Number: MFCD01137750
Linear Formula: C26H20N6
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C26H20N6/c27-19-5-1-3- |
InChI key | QROWVLFOWUYBIG-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | NC1=CC=CC(C(N2)=NC(C=C3)= |
solubility | DMSO: 10 mg/mL |
storage temp. | 2-8°C |
Biochem/physiol Actions: | DDRI-18 (DNA Damage Response Inhibitor-18) inhibits nonhomologous end-joining (NHEJ) DNA repair following double strand DNA breaks induced by ionizing radiation, and enhances the effects of DNA-damaging cancer drugs like etoposide, camptothecin and doxorubicin. |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H315 - H319 - H335 - H413 |
Precautionary statements | P273 - P302 + P352 - P305 + P351 + P338 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |