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W-13

SIGMA/SML0717 - ≥98% (HPLC)

Synonym: N-(4-Aminobutyl)-5-chloro-2-naphthalenesulfonamide hydrochloride; W13

CAS Number: 88519-57-7
Empirical Formula (Hill Notation): C14H17ClN2O2S · HCl
Molecular Weight: 349.28
MDL Number: MFCD00058030
Linear Formula: C14H17ClN2O2S · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0717-5MG 5 mg
 $87.90
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C14H17ClN2O2S.ClH/c15-13-7-3-6-12-11(13)5-4-8-14(12)20(18,19)17-10-2-1-9-16;/h3-8,17H,1-2,9-10,16H2;1H
InChI key IKMXJMNRHREPOD-UHFFFAOYSA-N
Quality Level 100 
SMILES string Cl.NCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12
solubility H2O: 20 mg/mL, clear
storage temp. room temp
Biochem/physiol Actions: W-13 has also been shown to inhibit the transcytosis of IgA, recycling of transferrin and overall alter the endocytic pathway in Madin-Darby canine kidney cells.
Biochem/physiol Actions: W-13 is a membrane-permeable calmodulin antagonist.
Biochem/physiol Actions: W-13 is a membrane-permeable calmodulin antagonist. W-13 inhibits Ca2+-calmodulin-dependent phosphodiesterase and has been shown to inhibit the EGF-dependent activation of EGFR in N7xHERc fibroblasts.
Features and Benefits: This compound is a featured product for Cyclic Nucleotide research. Click here  to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound is featured on the Phosphodiesterases  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352200

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