W-13
SIGMA/SML0717 - ≥98% (HPLC)
Synonym: N-
CAS Number: 88519-57-7
Empirical Formula (Hill Notation): C14H17ClN2O2S · HCl
Molecular Weight: 349.28
MDL Number: MFCD00058030
Linear Formula: C14H17ClN2O2S · HCl
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C14H17ClN2O2S.ClH/c15- |
InChI key | IKMXJMNRHREPOD-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | Cl.NCCCCNS(=O)(=O)c1cccc2 |
solubility | H2O: 20 mg/mL, clear |
storage temp. | room temp |
Biochem/physiol Actions: | W-13 has also been shown to inhibit the transcytosis of IgA, recycling of transferrin and overall alter the endocytic pathway in Madin-Darby canine kidney cells. |
Biochem/physiol Actions: | W-13 is a membrane-permeable calmodulin antagonist. W-13 inhibits Ca2+-calmodulin-dependent phosphodiesterase and has been shown to inhibit the EGF-dependent activation of EGFR in N7xHERc fibroblasts. |
Features and Benefits: | This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
Features and Benefits: | This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | room temp |
UNSPSC | 12352200 |