Synonym: 6,11-Dihydroxy-3,8-dimethoxy-1-methylbenzo[b]xanthene-7,10, 12-trione; Lycopersin; NSC 215139
CAS Number: 33390-21-5
Empirical Formula (Hill Notation): C20H14O8
Molecular Weight: 382.32
Linear Formula: C20H14O8
Product Type: Chemical
assay |
≥98% (HPLC) |
biological source |
Fusarium subglutinans |
form |
powder |
InChI |
1S/C20H14O8/c1-7-4-8(26-2)5-10-12(7)17(23)15-18(24)13-9(21)6-11(27-3)16(22)14(13)19(25)20(15)28-10/h4-6,24-25H,1-3H3 |
InChI key |
ZOQMSOSJEWBMHP-UHFFFAOYSA-N |
Quality Level |
200 |
solubility |
chloroform: 0.5 mg/mL |
|
dichloromethane: 0.5 mg/mL |
|
DMSO: 0.5 mg/mL (may require sonication and heating) |
storage temp. |
−20°C |
Biochem/physiol Actions: |
Bikaverin is a red pigment with a polyketide tetracyclic benzoxanthone structure. Bikaverin has an antibiotic activity against some protozoa and fungi and also inhibits Succinate- and NAD-linked respiration in rat mitochondria at 20 mg/mL. At higher concentrations (50 mg/mL) it acts as an oxidative phosphorylation uncoupling agent of tumor cells and isolated rat liver mitochondria. Bikaverin demonstrates antitumor activity on Erlich ascites carcinoma (EAC), leukemia and sarcoma cells. |
Reconstitution: |
Soluble in DMSO (0.5 mg/mL, may require sonication and heating). For further dilution, water based solutions can be used. Chloroform (0.5 mg/mL) and dichloromethane (0.5 mg/mL). |
Symbol |
GHS06 |
Signal word |
Danger |
Hazard statements |
H301 |
Precautionary statements |
P301 + P310 |
Hazard Codes |
T |
Risk Statements |
25 |
Safety Statements |
45 |
RIDADR |
UN 2811 6.1 / PGIII |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% (HPLC) |
Storage Temp. |
−20°C |
UNSPSC |
12352200 |