Synonym: (2-(2,2,6,6-Tetramethylpiperidin-1-oxyl-4-ylamino)-2-oxoethyl)triphenylphosphonium chloride; Mito-TEMPO
CAS Number: 1334850-99-5
Empirical Formula (Hill Notation): C29H35N2O2P · Cl
Molecular Weight: 510.03
Linear Formula: C29H35N2O2P · Cl
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: SML0737-25MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: SML0737-5MG
assay |
≥98% (HPLC) |
color |
white to light brown |
form |
powder |
Quality Level |
100 |
solubility |
H2O: 10 mg/mL, clear |
storage condition |
desiccated |
|
protect from light |
storage temp. |
−20°C |
Application: |
MitoTEMPO has been used as a mitochondria-targeted antioxidant. |
Biochem/physiol Actions: |
MitoTEMPO is a mitochondrially targeted antioxidant, a specific scavenger of mitochondrial superoxide. MitoTEMPO is a combination of the antioxidant piperidine nitroxide TEMPO with the lipophilic cation triphenylphosphonium, giving MitoTEMPO the ability to pass through lipid bilayers with ease and accumulate several hundred-fold in mitochondria. Mitochondrial dysfunction and oxidative stress contribute to a variety of disorders involving cardiovascular, kidney, liver disorders, Parkinson′s and Alzheimer′s disease. |
Other Notes: |
Light sensitive |
Packaging: |
5, 25 mg in glass bottle |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% (HPLC) |
Storage Temp. |
−20°C |
UNSPSC |
12352200 |