RORγ Activator 1b
SIGMA/SML0738 - ≥98% (HPLC)
Synonym: N-
CAS Number: 875286-88-7
Empirical Formula (Hill Notation): C15H14N2OS2
Molecular Weight: 302.41
Linear Formula: C15H14N2OS2
Product Type: Chemical
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| assay | ≥98% (HPLC) |
| color | white to beige |
| form | powder |
| Quality Level | 100  |
| solubility | DMSO: 20 mg/mL, clear |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | RORγ Activator 1b binds to the retinoid-related orphan receptor RORγ and induces IL-17 reporter gene expression with an EC50 of 0.1 μM. The compound RORγ Activator 1b enhances differentiation of CD4+ T cells to IL-17-secreting cells with a maximum effect of 220 percent of control at 3 μM. |
| Biochem/physiol Actions: | RORγ Activator 1b binds to the retinoid-related orphan receptor RORγ and induces IL-17 reporter gene expression. |
| Packaging: | 5, 25 mg in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |