(+)-CP-99994 dihydrochloride
SIGMA/SML0752 - ≥98% (HPLC)
Synonym: (2S,3S)
CAS Number: 145148-39-6
Empirical Formula (Hill Notation): C19H24N2O · 2HCl
Molecular Weight: 369.33
Linear Formula: C19H24N2O · 2HCl
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 |
solubility | H2O: 15 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | (+)-CP-99994 dihydrochloride is an effective and selective non-peptide substance P receptor antagonist. It is synthesized from allylic and homoallylic C-H diamination of 4-phenyl-1-butene. (+)-CP-99994 exhibits anti-emetic activity in ferrets. |
Biochem/physiol Actions: | (+)-CP-99994 is a selective neurokinin (NK)-1 tachykinin antagonist. (+)-CP-99994 binds selectively and with high affinity with a Ki of 0.25 nM in a human cell line. |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS09 |
Signal word | Warning |
Hazard statements | H410 |
Precautionary statements | P273 - P501 |
Hazard Codes | N |
Risk Statements | 50/53 |
Safety Statements | 60-61 |
RIDADR | UN 3077 9 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |