WS6

SIGMA/SML0757 - ≥98% (HPLC)

Synonym: 4-[[6-[(Cyclopropylcarbonyl)amino]-4-pyrimidinyl]oxy]-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzeneacetamide; WS-6

CAS Number: 1421227-53-3
Empirical Formula (Hill Notation): C₂₉H₃₁F₃N₆O₃
Molecular Weight: 568.59
Linear Formula: C₂₉H₃₁F₃N₆O₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML0757-5MG	5 mg	$142.00 1/EA	Add To Favorites
45-SML0757-25MG	25 mg	$0.00 1/EA CALL FOR PRICE	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
Quality Level	100
solubility	DMSO: 20 mg/mL, clear
storage temp.	2-8°C

Biochem/physiol Actions:	WS6 is an inducer of β cell proliferation, thought to act primarily through modulating the activities of the IKB kinase pathway and ErbB3-binding protein 1 (EBP1) also known as proliferation-associated protein 2G4 (PA2G4), an RNA-binding protein that is involved in growth regulation and inhibition.
Biochem/physiol Actions:	WS6 is an inducer of β cell proliferation, thought to act primarily through modulating the activities of the IKB kinase pathway and ErbB3-binding protein 1 (EBP1). WS6 is also known to stimulate human ɑ cell proliferation. WS6 does not affect β cell differentiation, as no alteration in the number of insulin producing β cells is observed
Features and Benefits:	This compound is featured on the EGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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