SR1555
SIGMA/SML0765 - ≥98% (HPLC)
Synonym: 1,1,1,3,3,3-
CAS Number: 1386439-51-5
Empirical Formula (Hill Notation): C22H22F6N2O2
Molecular Weight: 460.41
Linear Formula: C22H22F6N2O2
Product Type: Chemical
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| assay | ≥98% (HPLC) |
| color | white to beige |
| form | powder |
| Quality Level | 100  |
| solubility | DMSO: 15 mg/mL, clear |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | SR1555 is a selective RORγ inverse agonist that inhibits the development and function of TH17 cells, a subset of T cells that have been implicated in the pathology of several autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. SR1555 also increases the frequency of T regulatory cells, an effect not seen with previously described RORγ ligands. |
| Biochem/physiol Actions: | SR1555 is a selective RORγ inverse agonist. |
| Packaging: | 5, 25 mg in glass bottle |
| Hazard statements | H413 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |