LG100754
SIGMA/SML0771 - ≥98% (HPLC)
Synonym: (2E,4E,6Z)
CAS Number: 180713-37-5
Empirical Formula (Hill Notation): C26H36O3
Molecular Weight: 396.56
Linear Formula: C26H36O3
Product Type: Chemical
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This image depicts SML0771-5MG.
This image depicts SML0771-5MG.
| assay | ≥98% (HPLC) |
| color | white to beige |
| form | powder |
| InChI | 1S/C26H36O3/c1-8-14-29-23 |
| InChI key | HNODNXQAYXJFMQ-LQUSFLDPSA |
| Quality Level | 100  |
| SMILES string | O(CCC)c1cc2c(cc1C(=C/C=C |
| solubility | DMSO: 10 mg/mL, clear |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | LG100754 is a RXR:PPAR agonist. |
| Biochem/physiol Actions: | LG100754 is a unique RXR ligand that acts as an antagonist against RXR homodimers, but is a strong agonist for RXR:PPARα and RXR:PPARγ heterodimers. The compound does not have agonist activities for other RXR heterodimers containing LXR or GAR/FXR receptors. LG100754 initiates adipocyte differentiation, inhibits TNFα-induced insulin receptor hypophosphorylation and improves insulin resistance in db/db mice. |
| Features and Benefits: | This compound is featured on the InsR , Nuclear Receptors (Non-Steroids) and Nuclear Receptors (PPARs) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Packaging: | 5, 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |