GSK-650394

SIGMA/SML0773 - ≥98% (HPLC)

Synonym: 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-benzoic acid; GSK 650394; GSK650394

CAS Number: 890842-28-1
Empirical Formula (Hill Notation): C₂₅H₂₂N₂O₂
Molecular Weight: 382.45
Linear Formula: C₂₅H₂₂N₂O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SML0773-5MG	5 mg	$150.00 1/EA		Add To Favorites
45-SML0773-25MG	25 mg	$598.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C25H22N2O2/c28-25(29)20-11-10-18(12-21(20)17-8-4-5-9-17)23-15-27-24-22(23)13-19(14-26-24)16-6-2-1-3-7-16/h1-3,6-7,10-15,17H,4-5,8-9H2,(H,26,27)(H,28,29)
InChI key	WVSBGSNVCDAMCF-UHFFFAOYSA-N
Quality Level	100
solubility	DMSO: 20 mg/mL, clear
storage temp.	room temp

Application:	GSK-650394 has been used as a serum and glucocorticoid-activated kinase (SGK1) inhibitor.
Biochem/physiol Actions:	GSK-650394 has an IC₅₀ value of 62 nM for serum and glucocorticoid-activated kinase-1 (SGK1) and 103 nM for SGK2. It has an ability to stop viral replication at concentrations that are nontoxic to cells.
Biochem/physiol Actions:	GSK-650394 is a potent and selective Serum- and glucocorticoid-regulated kinase 1 (SGK1) antagonist.
Features and Benefits:	This compound is featured on the PKB/Akt page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	room temp
UNSPSC	12352200

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