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NSC109555

SIGMA/SML0781 - ≥98% (HPLC)

Synonym: 2,2′-[Carbonylbis(imino-4,1-phenyleneethylidyne)]-bis-Hydrazinecarboximidamide methanesulfonate (1:2)

CAS Number: 15427-93-7
Empirical Formula (Hill Notation): C19H24N10O · 2CH3SO3H
Molecular Weight: 600.67
Linear Formula: C19H24N10O · 2CH3SO3H
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0781-5MG 5 mg
 $0.00
1/EA
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45-SML0781-25MG 25 mg
 $0.00
1/EA
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C19H24N10O.2CH4O3S/c1-11(26-28-17(20)21)13-3-7-15(8-4-13)24-19(30)25-16-9-5-14(6-10-16)12(2)27-29-18(22)23;2*1-5(2,3)4/h3-10H,1-2H3,(H4,20,21,28)(H4,22,23,29)(H2,24,25,30);2*1H3,(H,2,3,4)/b26-11+,27-12+;;
InChI key HXDBGZUARNKHBV-XMDRLFCYSA-N
Quality Level 100 
solubility H2O: 5 mg/mL, clear (warmed)
storage temp. 2-8°C
Biochem/physiol Actions: NSC109555 is a selective inhibitor of Chk2 (IC50 = 310 nM). The compound is reversible and competitive for ATP, and displays little or no activity against other related kinases, including Chk1, at concentrations up to 10 μM.
Features and Benefits: This compound is featured on the Csk  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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