BMS-303141
SIGMA/SML0784 - ≥98% (HPLC)
Synonym: 3,5-
CAS Number: 943962-47-8
Empirical Formula (Hill Notation): C19H15Cl2NO4S
Molecular Weight: 424.30
MDL Number: MFCD25976797
Linear Formula: C19H15Cl2NO4S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 |
SMILES string | O=S(NC1=C(OC)C=CC(C2=CC=C |
solubility | DMSO: 20 mg/mL, clear |
storage temp. | 2-8°C |
Application: | BMS-303141 has been used for inhibition of ATP citrate lyase in breast cancer cell lines. |
Biochem/physiol Actions: | BMS-303141 is a potent inhibitor of ATP citrate lyase (ACL). BMS-303141 inhibits lipid synthesis in HepG2 cells with an IC50 of 8 μM, and lowers plasma triglycerides in a murine hyperlipdemia model. |
Packaging: | 5, 25 mg in glass bottle |
Hazard statements | H413 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |