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BMS-303141

SIGMA/SML0784 - ≥98% (HPLC)

Synonym: 3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1′-biphenyl]-3-yl)-benzenesulfonamide

CAS Number: 943962-47-8
Empirical Formula (Hill Notation): C19H15Cl2NO4S
Molecular Weight: 424.30
MDL Number: MFCD25976797
Linear Formula: C19H15Cl2NO4S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0784-5MG 5 mg
 $138.00
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45-SML0784-25MG 25 mg
 $559.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C19H15Cl2NO4S/c1-26-17-8-7-13(12-5-3-2-4-6-12)9-16(17)22-27(24,25)18-11-14(20)10-15(21)19(18)23/h2-11,22-23H,1H3
InChI key SIIPNDKXZOTLEA-UHFFFAOYSA-N
Quality Level 100 
SMILES string O=S(NC1=C(OC)C=CC(C2=CC=CC=C2)=C1)(C3=C(O)C(Cl)=CC(Cl)=C3)=O
solubility DMSO: 20 mg/mL, clear
storage temp. 2-8°C
Application: BMS-303141 has been used for inhibition of ATP citrate lyase in breast cancer cell lines.
Biochem/physiol Actions: BMS-303141 is a potent inhibitor of ATP citrate lyase (ACL).
Biochem/physiol Actions: BMS-303141 is a potent inhibitor of ATP citrate lyase (ACL). BMS-303141 inhibits lipid synthesis in HepG2 cells with an IC50 of 8 μM, and lowers plasma triglycerides in a murine hyperlipdemia model.
Packaging: 5, 25 mg in glass bottle
Hazard statements H413
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 51111800

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