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Decursin

SIGMA/SML0786 - ≥97% (HPLC)

Synonym: (+)-Decursin; (7S)-7,8-Dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b′]dipyran-7-yl 3-methyl-2-butenoate; 3-Methyl-2-butenoic acid (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-pyrano[3,2-g]-1-benzopyran-7-yl ester

CAS Number: 5928-25-6
Empirical Formula (Hill Notation): C19H20O5
Molecular Weight: 328.36
MDL Number: MFCD00272154
Linear Formula: C19H20O5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0786-1MG 1 mg
 $118.00
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45-SML0786-5MG 5 mg
 $468.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SML0786-5MG.

 

assay ≥97% (HPLC)
biological source Radix peucedani
color white to beige
form powder
InChI 1S/C19H20O5/c1-11(2)7-18(21)23-16-9-13-8-12-5-6-17(20)22-14(12)10-15(13)24-19(16,3)4/h5-8,10,16H,9H2,1-4H3/t16-/m0/s1
InChI key CUKSFECWKQBVED-INIZCTEOSA-N
optical activity [α]/D +120 to +160°, c = 0.5 in chloroform-d
Quality Level 100 
shipped in wet ice
SMILES string [o]1c2c(cc3c(c2)OC([C@H](C3)OC(=O)C=C(C)C)(C)C)cc[c]1=O
solubility DMSO: 5 mg/mL, clear
storage temp. −20°C
Biochem/physiol Actions: Decursin is a cumarin isolated from Radix peucedani that exhibits a number of physiological actions including anticancer, antibacterial, antinematodal and antioxidant.
Biochem/physiol Actions: Decursin is a cumarin isolated from Radix peucedani that exhibits a number of physiological actions including anticancer, antibacterial, antinematodal and antioxidant. Decursin is potent anti-angiogenic agent targeting the VEGFR-2 signaling pathway. Decursin exhibits potent neuroprotective activity against glutamate and Ab- induced neurotoxicity. Apparently, decursin stimulates activation of Nerf2. Also, decursin inhibits androgen stimulated AR translocation to the nucleus in LNCaP prostate cancer cells.
Features and Benefits: This compound is featured on the Nuclear Receptors (Steroids)  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 1, 5 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥97% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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