N,N-Dimethyltryptamine
SIGMA/SML0791 - ≥97% (HPLC)
Synonym: DMT; Dimethyltryptamine; N,N-
CAS Number: 61-50-7
Empirical Formula (Hill Notation): C12H16N2
Molecular Weight: 188.27
MDL Number: MFCD00055989
Linear Formula: C12H16N2
Product Type: Chemical
| assay | ≥97% (HPLC) |
| color | white to beige |
| drug control | USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal) |
| form | powder |
| InChI | 1S/C12H16N2/c1-14(2)8-7-1 |
| InChI key | DMULVCHRPCFFGV-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | CN(C)CCC1=CNC2=C1C=CC=C2 |
| solubility | DMSO: 15 mg/mL, clear |
| storage temp. | −20°C |
| Biochem/physiol Actions: | N,N-Dimethyltryptamine (DMT) functions as a hallucinogen. Experimental studies states that DMT is an endogenous sigma-1 receptor agonist. DMT interacts with sigma-1 receptors and blocks voltage-gated sodium ion (Na+) channels in both native cardiac myocytes and heterologous cells that contain sigma-1 receptors. |
| Biochem/physiol Actions: | N,N-Dimethyltryptamine (DMT) is a hallucinogen now known to be an endogenous sigma-1 receptor agonist. In keeping with the known sigma-1 receptor modulation of voltage gated Na+ channels, DMT was found to reversibly inhibit Na currents by 62% in vitro. N,N-Dimethyltryptamine also induced hypermotility in WT mice (but not in sigma-1 KO mice), all evidence of its sigma-1 agonist activity. |
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| Other Notes: | Product contains 1.2% wt. EtOH (by NMR and EA). |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H336 |
| Precautionary statements | P261 - P271 - P304 + P340 + P312 - P403 + P233 - P405 - P501 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352116 |