HI-TOPK-032
SIGMA/SML0796 - ≥98% (HPLC)
Synonym: N-
CAS Number: 487020-03-1
Empirical Formula (Hill Notation): C20H11N5OS
Molecular Weight: 369.40
Linear Formula: C20H11N5OS
Product Type: Chemical
assay | ≥98% (HPLC) |
color | orange to dark red |
form | powder |
Quality Level | 100 |
solubility | DMSO: 3 mg/mL, clear (warmed) |
storage temp. | 2-8°C |
Application: | HI-TOPK-032 has been used as a PDZ binding-kinase (PBK) inhibitor. |
Biochem/physiol Actions: | HI-TOPK-032 belongs to the class of ATP-competitive inhibitors. It can also be used as a potent therapeutic for colorectal cancer. |
Biochem/physiol Actions: | HI-TOPK-032 is a specific TOPK (T-LAK cell–originated protein kinase) inhibitor both in vitro and in vivo. HI-TOPK-032 suppressed tumor growth in a colon cancer xenograft model. |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Hazard Codes | Xn |
Risk Statements | 22 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |