Flibanserin
SIGMA/SML0797 - ≥98% (HPLC)
Synonym: 1,3-
CAS Number: 167933-07-5
Empirical Formula (Hill Notation): C20H21F3N4O
Molecular Weight: 390.40
Linear Formula: C20H21F3N4O
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C20H21F3N4O/c21-20(22, |
InChI key | CCIZQGRSEAHATK-UHFFFAOYSA |
Quality Level | 100 |
solubility | DMSO: 10 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Flibanserin is a 5-HT1A receptor agonist and 5-HT2A receptor antagonist. Flibanserin has high affinity for human 5-HT1A receptors (Ki = 1 nm) and lower affinity for 5-HT2A (Ki = 49 nm) and D4 (Ki = 4–24 nm) receptors, and negligible affinity for a variety of other neurotransmitter receptors and ion channels. Flibanserin was investigated as a novel, non-hormonal treatment for pre-menopausal women with Hypoactive Sexual Desire Disorder (HSDD). Flibanserin. Recently, Flibanserin was found to reduce L-DOPA-induced dyskinesia in a model of Parkinson′s Disease. |
Features and Benefits: | This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS06 |
Signal word | Danger |
Hazard statements | H301 - H315 - H319 - H335 |
Precautionary statements | P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 |
Hazard Codes | T |
Risk Statements | 25-36/37/38 |
Safety Statements | 26-45 |
RIDADR | UN 2811 6.1 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |