Flibanserin

SIGMA/SML0797 - ≥98% (HPLC)

Synonym: 1,3-Dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-2H-benzimidazol-2-one; BIMT 17; BIMT 17BS

CAS Number: 167933-07-5
Empirical Formula (Hill Notation): C₂₀H₂₁F₃N₄O
Molecular Weight: 390.40
Linear Formula: C₂₀H₂₁F₃N₄O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML0797-5MG	5 mg	$94.80 1/EA	Add To Favorites
45-SML0797-25MG	25 mg	$385.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C20H21F3N4O/c21-20(22,23)15-5-7-16(8-6-15)26-12-9-25(10-13-26)11-14-27-18-4-2-1-3-17(18)24-19(27)28/h1-8H,9-14H2,(H,24,28)
InChI key	CCIZQGRSEAHATK-UHFFFAOYSA-N
Quality Level	100
SMILES string	FC(F)(F)c1ccc(cc1)N2CCN(CC2)CC[n]3c4c([nH][c]3=O)cccc4
solubility	DMSO: 10 mg/mL, clear
storage temp.	2-8°C

Biochem/physiol Actions:	Flibanserin is a 5-HT1A receptor agonist and 5-HT2A receptor antagonist.
Biochem/physiol Actions:	Flibanserin is a 5-HT1A receptor agonist and 5-HT2A receptor antagonist. Flibanserin has high affinity for human 5-HT1A receptors (Ki = 1 nm) and lower affinity for 5-HT2A (Ki = 49 nm) and D4 (Ki = 4–24 nm) receptors, and negligible affinity for a variety of other neurotransmitter receptors and ion channels. Flibanserin was investigated as a novel, non-hormonal treatment for pre-menopausal women with Hypoactive Sexual Desire Disorder (HSDD). Flibanserin. Recently, Flibanserin was found to reduce L-DOPA-induced dyskinesia in a model of Parkinson′s Disease.
Features and Benefits:	This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Packaging:	5, 25 mg in glass bottle

Symbol	GHS06
Signal word	Danger
Hazard statements	H301 - H315 - H319 - H335
Precautionary statements	P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
Hazard Codes	T
Risk Statements	25-36/37/38
Safety Statements	26-45
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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