(S)-CPP sodium salt
SIGMA/SML0804 - ≥96% (HPLC)
Synonym: (S)
CAS Number: 194979-70-9
Empirical Formula (Hill Notation): C9H8ClO2 · Na
Molecular Weight: 206.60
MDL Number: MFCD28118980
Linear Formula: C9H8ClO2 · Na
Product Type: Chemical
assay | ≥96% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C9H9ClO2.Na/c10-8(9(11 |
InChI key | HMHPCHNNVOLTFC-QRPNPIFTSA |
Quality Level | 100 |
SMILES string | [O-]C([C@@H](Cl)CC1=CC=CC |
solubility | H2O: 20 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | (S)-CPP is an inhibitor of branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, also know as BDK, or keto acid dehydrogenase kinase. BDK is a negative regulator of BCKDC activity. Inhibition of BDK by (S)-CPP (IC50 = 6.3 μM) leads to complex activation, and significant reduction of plasma levels of leucine/isoleucine and valine in wild type mice. |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥96% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |